A Research Placement in Japan
During the summer of my fourth year of medical school, I had the opportunity to complete an 8-week research placement in Japan, at the University of Kyoto followed by a 2-week research placement at the University of Kyushu, both in their respective departments of Dermatology.
Despite having graduated from Kendrick School in 2021, I was fortunate to receive a travel grant of £500 from the Kendrick Trustees, which I was very grateful for.
At the University of Kyoto, I worked in 
Dr Kambe’s group whose research focussed on the role of a gene mutation in the pathophysiology of keloid scars. In this lab, I developed skills in molecular biology methods such as designing plasmids and primers, plasmid amplification, PCR, gel electrophoresis and DNA sequencing. In addition to laboratory research, I attended seminars where I learnt more about cellular senescence and atopic dermatitis.
At the University of Kyushu, I worked in Dr Yamamura’s group whose research focussed on the pathophysiology of Yusho disease, caused by ingestion of polychlorinated biphenyls. Yusho disease is prevalent in Kyushu due to the 1968 incident in North Kyushu where rice bran oil produced by Kanemi Company was contaminated with polychlorinated biphenyls and sold to the public. The effects of poisoning are still seen today, including amongst the children of those originally affected. Yusho disease has several manifestations, including acneform eruptions, hyperpigmentation of the skin and excessive sweating . As part of experiments researching this disease, I learnt how to culture skin cells, extract RNA and proteins, perform qPCR and Western blot.
In addition to the research, I had the opportunity to observe a skin graft procedure at the University of Kyushu. Healthy skin from the patient was used to replace an area where dermatofibrosarcoma protuberans (a rare type of skin malignancy) had been removed. Through observing surgery, I was able to get a better understanding of what dermatology is like in Japan compared to the UK.
As well as working in the labs, I was able to enjoy both Kyoto and Fukuoka during my free time. During the weekends, I enjoyed exploring the UNESCO World Heritage Sites in Kyoto, such as Kiyomizu-dera, Nijo Castle and Byodoin. I also had the opportunity to explore Kyoto with my colleagues from the lab. At the University of Kyushu, I was kindly invited to a barbecue event held in collaboration with the four medical schools in Fukuoka.
Overall, I greatly enjoyed my time in both Kyoto and Fukuoka. It was an incredible summer spending 10 weeks in my native Japan, and I left with new friends and colleagues, who I hope I will have the opportunity to work with in the future.
I would like to end this report by thanking the Kendrick Trustees for their funding towards this experience.
By Claudia Jimenez, Class of 2021